ginamdr4 0 Posted May 1, 2019 Hello! I am now on my second bout of panic disorder. This time with PTSD and depression. I had success with Zoloft in the past but have terrible worsening anxiety, agitation, and insomnia when I start. My doctor has started me on the lowest possible dose but I am still terrified. Has anyone else had this reaction? What did you do to get through it? Quote Share this post Link to post Share on other sites