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Memantine as an Augmentation Therapy for Anxiety Disorders

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Glutamate, an excitatory neurotransmitter in the central nervous system (CNS), may play a role in the development of anxiety. Memantine partially blocks N-methyl-D-aspartate (NMDA) receptors' glutamate channels located in the CNS. This paper evaluates memantine as an augmentation therapy for treatment of anxiety.

https://www.hindawi.com/journals/crips/2012/749796/

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